Knicks Visit Chicago as 7.5-Point Favorites Wednesday Night

The New York Knicks head to Chicago on Wednesday night for an Eastern Conference matchup against the Bulls.

Tipoff at United Center is set for 8 p.m. ET. The Knicks are 7.5-point favorites, and the over/under is 234.5. New York brings a 1-3 record after Tuesday's 111-97 win over Detroit. The Bulls also sit at 1-3 following a 134-99 loss at Boston on Monday. The Knicks are 0-1 on the road this season; the Bulls are 0-1 at home.

The SportsLine Projection Model has run 10,000 simulations of the game. The model's track record on top-rated NBA picks since 2018 shows nearly $19,000 in profit for $100 players, including five straight seasons of four-digit profit. Heading into Week 2 of the 2026-27 season, the model carries a 26-10 record, or 72%, on top-rated spread picks at NBA betting sites dating to last season.

New York's offense runs through guard Jalen Brunson and center Karl-Anthony Towns. Across four games, Brunson has averaged 22.8 points, 4.5 assists and 2.8 rebounds. Towns has posted 22.5 points, 14 rebounds and 2.8 assists per game. For Chicago, forward Caleb Wilson has averaged 21 points, 7.3 rebounds, 1.8 assists and 1.8 steals in 34 minutes.

Chicago's defense ranks 30th in the league, allowing 129.5 points per game. The model projects 238 combined points, with the over hitting 56% of the time. The over has landed in six of the last nine meetings between the two teams and has gone 3-1 in Bulls games this season. The model also indicates one side of the spread hits well over 60% of the time.

The Bulls finished fourth in the Central Division last season at 31-51. The Knicks finished second in the Atlantic Division at 53-29.